Published on September 25, 2024

Understanding glucose and fructose metabolism within the cell and the effect each substrate has on ATP, the energy currency, is not just for advanced horse owners. This knowledge is crucial to anyone caring for horses as it explains why Equine Metabolic Syndrome, Insulin resistance or dysregulation, misbehaving issues, and a generalized unwillingness are prevalent in every aspect of the horse industry.

Fructose is not just a dietary component but also produced in mammals through the Polyol Pathway. Its purpose is to prepare the horse for challenging times like winter. However, when produced throughout the year, fructose metabolism leads to depleted energy within the cell, increased cellular and body inflammation, body fat production, and heightened hunger and aggressive behavior. These are serious issues that every horse owner should be aware of and motivated to address.

Exercise is a key player in reducing the effects of fructose metabolism, but it’s not always feasible for many horses. However, controlling fructose intake and the triggers that convert glucose into fructose are practical, effective solutions that every horse owner can and should implement, empowering them to take control of their horse’s health.

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